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2026, 01, v.40 72-82
PM2.5诱导肺损伤的研究进展
基金项目(Foundation): 安徽省教育厅优青项目(2024AH030040); 安徽省大学生创新训练项目(S202410367155)
邮箱(Email):
DOI: 10.16421/j.cnki.1002-3127.2026.01.013
摘要:

PM2.5(fine particulate matter)是诱导肺部疾病,危害人类身体健康的重要影响因素,其与肺损伤的发生发展密切相关。本文介绍了PM2.5的污染现状,并从PM2.5的理化性质及组成成分出发,揭示了与PM2.5相关肺部疾病的发病机制,包括哮喘、慢性阻塞性肺病、肺炎及肺癌,并介绍了PM2.5对肺组织损伤的具体机制,包括免疫炎症反应、自噬和凋亡、铁死亡、氧化应激和遗传物质损伤等。本文总结近年来防治PM2.5的相关研究,旨在为肺部疾病的治疗提供新策略。

Abstract:

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参考文献

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基本信息:

DOI:10.16421/j.cnki.1002-3127.2026.01.013

中图分类号:R114

引用信息:

[1]王鹏镔,徐旋,马天浩,等.PM_(2.5)诱导肺损伤的研究进展[J].毒理学杂志,2026,40(01):72-82.DOI:10.16421/j.cnki.1002-3127.2026.01.013.

基金信息:

安徽省教育厅优青项目(2024AH030040); 安徽省大学生创新训练项目(S202410367155)

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