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2018 06 v.32 484-488
神经退行性疾病发病机制的研究进展
基金项目(Foundation): 国家自然科学基金(81673223);; 辽宁省教育厅(LK201615)
邮箱(Email):
DOI: 10.16421/j.cnki.1002-3127.2018.06.013
中文作者单位:

中国医科大学公共卫生学院卫生毒理教研室;

摘要(Abstract):

<正>神经退行性疾病(Neurodegenerative diseases)是以发作迟缓和选择性神经元的功能障碍为特征表现,由于大脑和脊髓的神经元细胞丧失而引起的一类不可逆转的神经系统疾病,主要包括阿尔茨海默病(Alzheimer disease,AD)、帕金森氏病(Parkinson’s disease,PD)和亨廷顿氏病(Huntington’s disease,HD)等[1]。这些疾病临床表现均为认知功能下降,虽然其具有不同的组织病理学

关键词(KeyWords): 神经退行性疾病;;蛋白异常聚积;;氧化应激;;DNA损伤修复;;能量代谢障碍
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基本信息:

DOI:10.16421/j.cnki.1002-3127.2018.06.013

中图分类号:R741

引用信息:

[1]吴卉,靳翠红.神经退行性疾病发病机制的研究进展[J].毒理学杂志,2018,32(06):484-488.DOI:10.16421/j.cnki.1002-3127.2018.06.013.

基金信息:

国家自然科学基金(81673223);; 辽宁省教育厅(LK201615)

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